Background and Study Aims: Endoscopic sclerotherapy (EST) results in an increase in
the prevalence of portal hypertensive gastropathy (PHG). However, the effects of sclerotherapy
on hemorrhoids, anorectal or colonic varices and portal hypertensive colopathy are
not known. The aim of this study was to investigate these effects.
Patients and Methods: A total of 39 patients with portal hypertension were studied.
Upper gastrointestinal endoscopy and full-length colonoscopy were carried out before
the patients underwent EST for esophageal varices, and after obliteration of the varices
following sclerotherapy.
Results: The obliteration of esophageal varices by EST did not significantly affect
the prevalence of hemorrhoids (32 % before and after), anorectal varices (45 % before
and after) or portal hypertensive colopathy (60.5 % before and 66 % after, P > 0.05).
Conclusion: Obliteration of esophageal varices does not affect the prevalence of hemorrhoids,
anorectal varices, or portal hypertensive colopathy.
References
- 1
McCormack T T, Sims J, Eyre-Brook I, et al.
Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy?.
Gut.
1985;
26
1226-1232
- 2
Misra S P, Dwivedi M, Misra V, et al.
Endoscopic and histological appearance of the gastric mucosa in patients with portal
hypertension.
Gastrointest Endosc.
1990;
36
575-579
- 3
Viggiano T R, Gostout C J.
Portal hypertensive intestinal vasculopathy: a review of the clinical, endoscopic
and histopathological features.
Am J Gastroenterol.
1992;
87
944-954
- 4
Kozarek R A, Botoman V A, Bredfeldt J E, et al.
Portal colopathy: prospective study in patients with portal hypertension.
Gastroenterology.
1991;
101
1192-1197
- 5
Naveau S, Bedossa P, Poynard T, et al.
Portal hypertensive colopathy. A new entity.
Dig Dis Sci.
1991;
36
1774-1781
- 6
Scandalis N, Archimandritis A, Kastanas K, et al.
Colon findings in cirrhotics with portal hypertension. A prospective colonoscopic
and histological study.
J Clin Gastroenterol.
1994;
18
325-328
- 7
Chen L S, Lin H C, Lee F Y, et al.
Portal hypertensive colopathy in patients with cirrhosis.
Scand J Gastroenterol.
1996;
31
490-494
- 8
Ganguly S, Sarin S K, Bahtia V, Lahoti D.
The prevalence and spectrum of colonic lesions in patients with cirrhotic and noncirrhotic
portal hypertension.
Hepatology.
1995;
21
1226-1231
- 9
Misra S P, Dwivedi M, Misra V.
Prevalence and factors influencing hemorrhoids, anorectal varices and colopathy in
patients with portal hypertension.
Endoscopy.
1996;
29
340-345
- 10
Eleftheriadis E, Kotazampassi K, Karakavelas G, et al.
Portal hypertensive colopathy: endoscopic, hemodynamic and morphometric study.
Dig Endosc.
1993;
5
224-230
- 11
Rabinowitz M, Schade P R, Didzans V J, et al.
Colonic disease in cirrhosis: a endoscopic evaluation in 412 patients.
Gastroenterology.
1990;
99
195-199
- 12
Conn H O.
Ammonia tolerance in the diagnosis of esophageal varices. A comparison of endoscopic,
radiologic, and biochemical techniques.
J Lab Clin Med.
1967;
70
442-449
- 13
Pugh R NH, Murray-Lyon J M, Dawson J L, et al.
Transection of the esophagus for bleeding oesophageal varices.
Br J Surg.
1973;
60
646-649
- 14
Iwao T, Toyonaga A, Oho K, et al.
Portal hypertensive gastropathy develops less in patients with cirrhosis and fundal
varices.
J Hepatol.
1997;
26
1235-1241
- 15
Misra V, Misra S P, Dwivedi M, Gupta S C.
Histomorphometric study of portal hypertensive enteropathy.
Am J Clin Path.
1997;
108
652-657
- 16
Foutch P G, Sivak M V, Jr.
Colonic variceal hemorrhage after endoscopic injection sclerosis of esophageal varices:
a report of three cases.
Am J Gastroenterol.
1984;
79
756-760
S. P. MisraM.D. D.M. F.N.A.Sc.
Department of Gastroenterology
MLN Medical College
Allahabad 211 001
India
Phone: + 91-532-611420
Email: spmisra@nde.vsnl.net.in